Day surgical anaesthesia: Which patients? Which procedures?

which city? which right? for which peoples?

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Head injury: which patients need imaging? Which test is best?

Some patients with head injuries definitely need to undergo an imaging study--usually computed tomography (CT). Most, however, are in a category of "apparently mild" injury, and controversy continues about which of them need to undergo imaging studies to rule out intracranial injuries.

Clinical trials of stroke therapy: which cells, which patients?

Cardioprotective properties of fibrates: which fibrate, which patients, what mechanism?

Several large intervention trials have investigated the potential of fibrates to reduce cardiovascular events. The results have varied widely: positive, with gemfibrozil in the primary prevention Helsinki Heart Study (HHS)1 and the secondary prevention Veterans Administration High Density Lipoprotein Intervention Trial (VA-HIT)2; positive, with reservations related to an increase in noncardiova...

Which molecular targets are most relevant to general anaesthesia?

1. In view of the large number of possible molecular targets of general anaesthetics, it is necessary to have some criteria for judging which targets are important for producing general anaesthesia and which are probably not. 2. We consider in detail two criteria: sensitivity to clinically relevant concentrations of anaesthetics and stereoselectivity to anaesthetic optical isomers. 3. The targe...